By Egidio Del Fabbro, Akio Inui, Florian Strasser, David Blum, Hajime Suzuki
Cancer Cachexia is a concise, absolutely illustrated guide written with the purpose of accelerating expertise of melanoma cachexia and highlighting top perform analysis, remedy, and administration thoughts for this devastating affliction. this can be one other identify within the ongoing Springer Healthcare melanoma Supportive Care Series.
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Extra resources for Cancer Cachexia
Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation. 2000;102:2165-2168. 72 Pasceri V, Cheng JS, Chang J, 5. Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation. 2001;103:2531-2534. 73 Mantovani G, Anker SD, Inui A, et al. In: Mantovani G, Anker SD, Inui A, et al, eds. Cachexia and Wasting: A Modern Approach. Milano: Springer Milan; 2006:563-579. 74 Straus DS, Pascual G, Li M, et al.
Curr Opin Support Palliat Care. 2011;5:361-364. 6 Radbruch L, Elsner F, Trottenberg P, Strasser F, Fearon K. Clinical practice guidelines on cancer cachexia in advanced cancer patients. European Palliative Care Research Collaborative; 2010. id=ternkkdsszelxevzgtkb. Accessed July 16, 2012. 7 Evans WJ, Morley JE, Argiles J, et al. Cachexia: a new definition. Clin Nutr. 2008;101:8E-10E. 8 Ross R, Janssen I. Computer tomography and magnetic resonance imaging. In: Heymsfield S, Lohman T, Wang Z, Going S, eds.
Dronabinol has been used as an antiemetic in cancer for some time and has demonstrated efficacy in treating chemotherapy-induced nausea and vomiting . Several studies of THC in advanced cancer-associated anorexia have shown some improvement in mood and appetite, with either no or some improvement in body weight [11,12]. However, randomized controlled trials are needed to better determine the efficacy and usefulness of THC in cancer cachexia. The effects of cannabinoids are mediated via specific receptors and two types of cannabinoid receptors, CB1 and CB2, have been detected .